The Biochemistry and Physiology of Bone by Geoffrey H. Bourne download in ePub, pdf, iPad
For evolutionary studies, comparative biochemistry employs genes, proteins and enzymes. Woven bone is weaker than lamellar bone. Bone resorption typically exceeds bone formation on the endosteal surface, so the marrow space normally expands with aging.
Realizing the potential of Open Access, in recent years, there has been a tremendous boost to Open Access movement through various Open Access publishers. This information lays the groundwork for understanding the utility and clinical applications of iliac crest bone biopsy. Introduction Bone is a metabolically active tissue that undergoes continuous remodelling by two counteracting processes, namely bone formation and bone resorption. The diaphysis is composed primarily of dense cortical bone, whereas the metaphysis and epiphysis are composed of trabecular meshwork bone surrounded by a relatively thin shell of dense cortical bone.
Bone remodeling increases in perimenopausal and early postmenopausal women and then slows with further aging, but continues at a faster rate than in premenopausal women. This balance is achieved and regulated through the action of various systemic hormones e. Trabecular osteons are called packets.
The skeleton serves a variety of functions. The remodeling process resorbs old bone and forms new bone to prevent accumulation of bone microdamage.
Requests to do so should be addressed to the Editor. However, such techniques should be used with at most caution as they involve serious implications. Osteoclast recruitment, activation, and bone resorption is discussed in some detail, followed by a review of osteoblast recruitment and the process of new bone formation.
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